ELASPIC home << Job #oncokb << P38398.F79S
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P38398.F79S

Detailed results for job #oncokb produced by ELASPIC
P38398, Breast cancer type 1 susceptibility protein:
F79S
1
1863
zf..
BRCT
BRCA1 isoform 4, Isoform 4 of Breast cancer type 1 susceptibility protein:
1
1846
z..
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P38398.F79S

Completed successfully

Protein, domain: P38398 zf-C3HC4

Interacting with: BRCA1 isoform 4 zf-C3HC4

PDB templates used: 1jm7_A, 1jm7_B

Seq identity: 1.000, 0.250 Model score: 0.513

ELASPIC ΔΔG: 1.675

ELASPIC2 (EL2) score: 1.079

Mutation run by user.

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Citation

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