ELASPIC home << Job #oncokb << P37173.E526Q
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P37173.E526Q

Detailed results for job #oncokb produced by ELASPIC
P37173, TGF-beta receptor type-2:
E526Q
1
567
ecTbetaR2
Pkinase
KS6B1 isoform 2, Isoform Alpha II of Ribosomal protein S6 kinase beta-1:
1
502
Pkinase+Pkinase_C
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P37173.E526Q

Completed successfully

Protein, domain: P37173 Pkinase

Interacting with: KS6B1 isoform 2 Pkinase+Pkinase_C

PDB templates used: 3a60_A, 3a60_B

Seq identity: 0.241, 0.885 Model score: 0.362

ELASPIC ΔΔG: -0.179

ELASPIC2 (EL2) score: 0.474

Mutation in databases: ClinVar, UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.