ELASPIC home << Job #oncokb << P35968.R961W
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P35968.R961W

Detailed results for job #oncokb produced by ELASPIC
P35968, Vascular endothelial growth factor receptor 2:
R961W
1
1356
Pkinase_Tyr
V-set
I-set
Ig_2
I-set
FYN, Tyrosine-protein kinase Fyn:
1
537
Pkinase_Tyr
SH3_1
SH2
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Protein: P35968 | FYN | Cofactors | All
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P35968.R961W

Completed successfully

Protein, domain: P35968 Pkinase_Tyr

Interacting with: FYN Pkinase_Tyr

PDB templates used: 2og8_B, 2og8_A

Seq identity: 0.308, 0.637 Model score: 0.353

ELASPIC ΔΔG: 0.764

ELASPIC2 (EL2) score: 0.436

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

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