ELASPIC home << Job #oncokb << P35222.K335I
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P35222.K335I

Detailed results for job #oncokb produced by ELASPIC
P35222, Catenin beta-1:
K335I
1
781
Arm
AXIN1, Axin-1:
1
862
RGS
DIX
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Protein: P35222 | AXIN1 | Cofactors | All
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P35222.K335I

Completed successfully

Protein, domain: P35222 Arm

Interacting with: AXIN1 Axin_b-cat_bind

PDB templates used: 1qz7_A, 1qz7_B

Seq identity: 1.000, 0.882 Model score: -1.216

ELASPIC ΔΔG: 3.890

ELASPIC2 (EL2) score: 1.757

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.