ELASPIC home << Job #oncokb << P31751.H355M
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P31751.H355M

Detailed results for job #oncokb produced by ELASPIC
P31751, RAC-beta serine/threonine-protein kinase:
H355M
1
481
PH
Pkinase+Pkinase_C
GSK3B isoform 2, Isoform 2 of Glycogen synthase kinase-3 beta:
1
433
Pkinase
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P31751.H355M

Completed successfully

Protein, domain: P31751 Pkinase+Pkinase_C

Interacting with: GSK3B isoform 2 Pkinase

PDB templates used: 1i09_A, 1i09_B

Seq identity: 0.271, 0.950 Model score: 0.171

ELASPIC ΔΔG: 2.004

ELASPIC2 (EL2) score: 1.747

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.