ELASPIC home << Job #oncokb << P31751.H355M
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P31751.H355M

Detailed results for job #oncokb produced by ELASPIC
P31751, RAC-beta serine/threonine-protein kinase:
H355M
1
481
PH
Pkinase+Pkinase_C
SHAN3 isoform 3, Isoform 2 of SH3 and multiple ankyrin repeat domains protein 3:
1
1612
S..
PDZ
Ank_2+A..
..
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P31751.H355M

Completed successfully

Protein, domain: P31751 Pkinase+Pkinase_C

Interacting with: SHAN3 isoform 3 Ank_2+Ank_2

PDB templates used: 3zu7_A, 3zu7_B

Seq identity: 0.287, 0.310 Model score: 1.058

ELASPIC ΔΔG: 2.195

ELASPIC2 (EL2) score: 1.461

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.