ELASPIC home << Job #oncokb << P31751.H355M
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P31751.H355M

Detailed results for job #oncokb produced by ELASPIC
P31751, RAC-beta serine/threonine-protein kinase:
H355M
1
481
PH
Pkinase+Pkinase_C
MARK2 isoform 10, Isoform 10 of Serine/threonine-protein kinase MARK2:
1
686
Pkinase
KA1
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P31751.H355M

Completed successfully

Protein, domain: P31751 Pkinase+Pkinase_C

Interacting with: MARK2 isoform 10 Pkinase

PDB templates used: 1y8g_A, 1y8g_B

Seq identity: 0.359, 0.945 Model score: 0.625

ELASPIC ΔΔG: 0.998

ELASPIC2 (EL2) score: 1.241

Mutation run by user.

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Citation

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