ELASPIC home << Job #oncokb << P31751.H355M
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P31751.H355M

Detailed results for job #oncokb produced by ELASPIC
P31751, RAC-beta serine/threonine-protein kinase:
H355M
1
481
PH
Pkinase+Pkinase_C
AKT1, RAC-alpha serine/threonine-protein kinase:
1
480
PH
Pkinase+Pkinase_C
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Protein: P31751 | AKT1 | Cofactors | All
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P31751.H355M

Completed successfully

Protein, domain: P31751 Pkinase+Pkinase_C

Interacting with: AKT1 Pkinase+Pkinase_C

PDB templates used: 3iw4_B, 3iw4_A

Seq identity: 0.460, 0.468 Model score: 0.063

ELASPIC ΔΔG: 0.670

ELASPIC2 (EL2) score: 1.703

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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