ELASPIC home << Job #oncokb << P31749.L362R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P31749.L362R

Detailed results for job #oncokb produced by ELASPIC
P31749, RAC-alpha serine/threonine-protein kinase:
L362R
1
480
PH
Pkinase+Pkinase_C
RHEBL1, GTPase RhebL1:
1
183
Ras
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Protein: P31749 | RHEBL1 | Cofactors | All
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P31749.L362R

Completed successfully

Protein, domain: P31749 Pkinase+Pkinase_C

Interacting with: RHEBL1 Ras

PDB templates used: 2v55_C, 2v55_D

Seq identity: 0.372, 0.259 Model score: 0.282

ELASPIC ΔΔG: 0.846

ELASPIC2 (EL2) score: 2.019

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.