ELASPIC home << Job #oncokb << P31749.L362R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P31749.L362R

Detailed results for job #oncokb produced by ELASPIC
P31749, RAC-alpha serine/threonine-protein kinase:
L362R
1
480
PH
Pkinase+Pkinase_C
CAMKK1, Calcium/calmodulin-dependent protein kinase kinase 1:
1
505
Pkinase
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Model: Wild-type | Mutant | Both
Protein: P31749 | CAMKK1 | Cofactors | All
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P31749.L362R

Completed successfully

Protein, domain: P31749 Pkinase+Pkinase_C

Interacting with: CAMKK1 Pkinase

PDB templates used: 3o7l_B, 3o7l_D

Seq identity: 0.428, 0.319 Model score: 0.367

ELASPIC ΔΔG: 2.010

ELASPIC2 (EL2) score: 2.064

Mutation run by user.

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Citation

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