ELASPIC home << Job #oncokb << P31749.D323H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P31749.D323H

Detailed results for job #oncokb produced by ELASPIC
P31749, RAC-alpha serine/threonine-protein kinase:
D323H
1
480
PH
Pkinase+Pkinase_C
PPM1A isoform 2, Isoform Alpha-2 of Protein phosphatase 1A:
1
324
PP2C
PP2C_C
Select affected interaction:

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P31749.D323H

Completed successfully

Protein, domain: P31749 Pkinase+Pkinase_C

Interacting with: PPM1A isoform 2 PP2C

PDB templates used: 3ujg_A, 3ujg_B

Seq identity: 0.340, 0.344 Model score: 0.828

ELASPIC ΔΔG: 1.395

ELASPIC2 (EL2) score: 1.285

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.