ELASPIC home << Job #oncokb << P29992.R183C
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P29992.R183C

Detailed results for job #oncokb produced by ELASPIC
P29992, Guanine nucleotide-binding protein subunit alpha-11:
R183C
1
359
G-alpha
RGS14 isoform 5, Isoform 3 of Regulator of G-protein signaling 14:
1
414
GoLoco
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P29992.R183C

Completed successfully

Protein, domain: P29992 G-alpha

Interacting with: RGS14 isoform 5 GoLoco

PDB templates used: 3onw_A, 3onw_C

Seq identity: 0.532, 1.000 Model score: -0.052

ELASPIC ΔΔG: 2.176

ELASPIC2 (EL2) score: 1.908

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.