ELASPIC home << Job #oncokb << P27986.K379E
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P27986.K379E

Detailed results for job #oncokb produced by ELASPIC
P27986, Phosphatidylinositol 3-kinase regulatory subunit alpha:
K379E
1
724
SH3_2
SH2
RhoGAP
SH2

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P27986.K379E

Completed successfully

Protein, domain: P27986 SH2

Type: Core (stability)

PDB template used: 4ovv_B

Seq identity: 1.000 Model score: -0.777

ELASPIC ΔΔG: 0.838

ELASPIC2 (EL2) score: 1.799

Mutation in databases: COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.