ELASPIC home << Job #oncokb << P21860.P262H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P21860.P262H

Detailed results for job #oncokb produced by ELASPIC
P21860, Receptor tyrosine-protein kinase erbB-3:
P262H
1
1342
Pkinase_Tyr
Recep_..
Furin-l..
Recep_L_..
GF_re..
EGFR isoform 2, Isoform 2 of Epidermal growth factor receptor:
1
405
Recep_L_domain
Furin-like
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P21860.P262H

Completed successfully

Protein, domain: P21860 Furin-like

Interacting with: EGFR isoform 2 Furin-like

PDB templates used: 1ivo_B, 1ivo_A

Seq identity: 0.487, 1.000 Model score: 1.095

ELASPIC ΔΔG: 1.169

ELASPIC2 (EL2) score: 1.195

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.