ELASPIC home << Job #oncokb << P21802.R678G
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P21802.R678G

Detailed results for job #oncokb produced by ELASPIC
P21802, Fibroblast growth factor receptor 2:
R678G
1
821
I-set
I-set
Pkinase_Tyr
PPM1A isoform 3, Isoform 3 of Protein phosphatase 1A:
1
455
PP2C
PP2C_C
Select affected interaction:

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P21802.R678G

Completed successfully

Protein, domain: P21802 Pkinase_Tyr

Interacting with: PPM1A isoform 3 PP2C

PDB templates used: 3ujg_A, 3ujg_B

Seq identity: 0.286, 0.344 Model score: 0.765

ELASPIC ΔΔG:

ELASPIC2 (EL2) score: 1.176

Mutation in databases: UniProt, COSMIC, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.