ELASPIC home << Job #oncokb << P21802.K659N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P21802.K659N

Detailed results for job #oncokb produced by ELASPIC
P21802, Fibroblast growth factor receptor 2:
K659N
1
821
I-set
I-set
Pkinase_Tyr
PPM1A, Protein phosphatase 1A:
1
382
PP2C
PP2C_C
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Protein: P21802 | PPM1A | Cofactors | All
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P21802.K659N

Completed successfully

Protein, domain: P21802 Pkinase_Tyr

Interacting with: PPM1A PP2C

PDB templates used: 3ujg_A, 3ujg_B

Seq identity: 0.286, 0.344 Model score: 0.427

ELASPIC ΔΔG: 0.566

ELASPIC2 (EL2) score: 0.972

Mutation in databases: UniProt, COSMIC, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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