ELASPIC home << Job #oncokb << P16234.R748G
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P16234.R748G

Detailed results for job #oncokb produced by ELASPIC
P16234, Platelet-derived growth factor receptor alpha:
R748G
1
1089
Pkinase_Tyr
Ig_2
I-set
PDGFRA, Platelet-derived growth factor receptor alpha:
1
1089
Pkinase_Tyr
Ig_2
I-set
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Protein: P16234 | PDGFRA | Cofactors | All
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P16234.R748G

Completed successfully

Protein, domain: P16234 Pkinase_Tyr

Interacting with: PDGFRA Pkinase_Tyr

PDB templates used: 2pvy_B, 2pvy_C

Seq identity: 0.554, 0.548 Model score: 0.854

ELASPIC ΔΔG: 0.134

ELASPIC2 (EL2) score: -1.047

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

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