ELASPIC home << Job #oncokb << P16234.A633V
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P16234.A633V

Detailed results for job #oncokb produced by ELASPIC
P16234, Platelet-derived growth factor receptor alpha:
A633V
1
1089
Pkinase_Tyr
Ig_2
I-set
TGFR2 isoform 2, Isoform 2 of TGF-beta receptor type-2:
1
592
Pkinase
ecTbetaR2
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P16234.A633V

Completed successfully

Protein, domain: P16234 Pkinase_Tyr

Interacting with: TGFR2 isoform 2 Pkinase

PDB templates used: 3kxx_B, 3kxx_C

Seq identity: 0.541, 0.280 Model score: 0.564

ELASPIC ΔΔG: -0.219

ELASPIC2 (EL2) score: 1.374

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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