ELASPIC home << Job #oncokb << P15172.L122R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P15172.L122R

Detailed results for job #oncokb produced by ELASPIC
P15172, Myoblast determination protein 1:
L122R
1
320
HLH
HEY1, Hairy/enhancer-of-split related with YRPW motif protein 1:
1
304
HLH
Hairy_orange
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Protein: P15172 | HEY1 | Cofactors | All
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P15172.L122R

Completed successfully

Protein, domain: P15172 HLH

Interacting with: HEY1 HLH

PDB templates used: 2mh3_A, 2mh3_B

Seq identity: 0.259, 0.521 Model score: -0.373

ELASPIC ΔΔG: 2.841

ELASPIC2 (EL2) score: 2.713

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.