ELASPIC home << Job #oncokb << P15172.L122R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P15172.L122R

Detailed results for job #oncokb produced by ELASPIC
P15172, Myoblast determination protein 1:
L122R
1
320
HLH
ID3, DNA-binding protein inhibitor ID-3:
1
119
HLH
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Model: Wild-type | Mutant | Both
Protein: P15172 | ID3 | Cofactors | All
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P15172.L122R

Completed successfully

Protein, domain: P15172 HLH

Interacting with: ID3 HLH

PDB templates used: 2ql2_A, 2ql2_B

Seq identity: 0.397, 0.286 Model score: -0.995

ELASPIC ΔΔG: 1.209

ELASPIC2 (EL2) score: 2.601

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.