ELASPIC home << Job #oncokb << P15056.Y472C
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P15056.Y472C

Detailed results for job #oncokb produced by ELASPIC
P15056, Serine/threonine-protein kinase B-raf:
Y472C
1
766
RBD
C1_1
Pkinase_Tyr
MAPK1, Mitogen-activated protein kinase 1:
1
360
Pkinase
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Protein: P15056 | MAPK1 | Cofactors | All
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P15056.Y472C

Completed successfully

Protein, domain: P15056 Pkinase_Tyr

Interacting with: MAPK1 Pkinase

PDB templates used: 2fys_B, 2fys_A

Seq identity: 0.257, 0.994 Model score: 0.271

ELASPIC ΔΔG: 1.501

ELASPIC2 (EL2) score: 1.506

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

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