ELASPIC home << Job #oncokb << P15056.R671Q
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P15056.R671Q

Detailed results for job #oncokb produced by ELASPIC
P15056, Serine/threonine-protein kinase B-raf:
R671Q
1
766
RBD
C1_1
Pkinase_Tyr

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P15056.R671Q

Completed successfully

Protein, domain: P15056 Pkinase_Tyr

Type: Core (stability)

PDB template used: 4ksq_B

Seq identity: 1.000 Model score: -0.497

ELASPIC ΔΔG: 0.653

ELASPIC2 (EL2) score: -0.370

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.