ELASPIC home << Job #oncokb << P15056.R509H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P15056.R509H

Detailed results for job #oncokb produced by ELASPIC
P15056, Serine/threonine-protein kinase B-raf:
R509H
1
766
RBD
C1_1
Pkinase_Tyr
RAF1, RAF proto-oncogene serine/threonine-protein kinase:
1
648
RBD
C1_1
Pkinase_Tyr
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Protein: P15056 | RAF1 | Cofactors | All
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P15056.R509H

Completed successfully

Protein, domain: P15056 Pkinase_Tyr

Interacting with: RAF1 Pkinase_Tyr

PDB templates used: 4h58_C, 4h58_A

Seq identity: 0.993, 0.777 Model score: -0.536

ELASPIC ΔΔG: 4.972

ELASPIC2 (EL2) score: 1.694

Mutation run by user.

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Citation

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