ELASPIC home << Job #oncokb << P15056.R509H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P15056.R509H

Detailed results for job #oncokb produced by ELASPIC
P15056, Serine/threonine-protein kinase B-raf:
R509H
1
766
RBD
C1_1
Pkinase_Tyr
MAP3K1, Mitogen-activated protein kinase kinase kinase 1:
1
1512
Pkinase
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Protein: P15056 | MAP3K1 | Cofactors | All
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P15056.R509H

Completed successfully

Protein, domain: P15056 Pkinase_Tyr

Interacting with: MAP3K1 Pkinase

PDB templates used: 4e26_B, 4e26_A

Seq identity: 0.960, 0.275 Model score: -0.221

ELASPIC ΔΔG: 0.947

ELASPIC2 (EL2) score: 2.054

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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