ELASPIC home << Job #oncokb << P15056.G466E
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P15056.G466E

Detailed results for job #oncokb produced by ELASPIC
P15056, Serine/threonine-protein kinase B-raf:
G466E
1
766
RBD
C1_1
Pkinase_Tyr
PRKCA, Protein kinase C alpha type:
1
672
C2
C1_1
Pkinase+Pkinase_C
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Protein: P15056 | PRKCA | Cofactors | All
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P15056.G466E

Completed successfully

Protein, domain: P15056 Pkinase_Tyr

Interacting with: PRKCA Pkinase+Pkinase_C

PDB templates used: 3iw4_B, 3iw4_A

Seq identity: 0.276, 0.969 Model score: 0.370

ELASPIC ΔΔG: 1.868

ELASPIC2 (EL2) score: 2.101

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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