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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P10398.F351L

Detailed results for job #oncokb produced by ELASPIC

P10398, Serine/threonine-protein kinase A-Raf:
F351L
1
606
FKBP5 isoform 2, Isoform 2 of Peptidyl-prolyl cis-trans isomerase FKBP5:
1
268
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P10398.F351L

Completed successfully

Protein, domain: P10398 Pkinase_Tyr

Interacting with: FKBP5 isoform 2 FKBP_C

PDB templates used: 3mdy_C, 3mdy_D

Seq identity: 0.322, 0.500 Model score: 0.802

ELASPIC ΔΔG: 1.740

ELASPIC2 (EL2) score: 0.613

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation


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