ELASPIC home << Job #oncokb << P09619.P660T
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P09619.P660T

Detailed results for job #oncokb produced by ELASPIC
P09619, Platelet-derived growth factor receptor beta:
P660T
1
1106
ig
Ig_2
I-set
Pkinase_Tyr
RAF1 isoform 2, Isoform 2 of RAF proto-oncogene serine/threonine-protein kinase:
1
668
Pkinase_Tyr
RBD
C1_1
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P09619.P660T

Completed successfully

Protein, domain: P09619 Pkinase_Tyr

Interacting with: RAF1 isoform 2 Pkinase_Tyr

PDB templates used: 4e26_B, 4e26_A

Seq identity: 0.333, 0.788 Model score: 0.670

ELASPIC ΔΔG: 2.268

ELASPIC2 (EL2) score: 0.185

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.