ELASPIC home << Job #oncokb << P08922.G1971E
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P08922.G1971E

Detailed results for job #oncokb produced by ELASPIC
P08922, Proto-oncogene tyrosine-protein kinase ROS:
G1971E
1
2347
fn3
fn3
Pkinase_..
fn3
..
EGFR, Epidermal growth factor receptor:
1
1210
Recep_L_d..
Recep_..
Furin..
Pkinase_Tyr
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Protein: P08922 | EGFR | Cofactors | All
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P08922.G1971E

Completed successfully

Protein, domain: P08922 Pkinase_Tyr

Interacting with: EGFR Pkinase_Tyr

PDB templates used: 4i24_A, 4i24_B

Seq identity: 0.382, 0.962 Model score: -0.289

ELASPIC ΔΔG: 1.402

ELASPIC2 (EL2) score: 0.142

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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