ELASPIC home << Job #oncokb << P08069.M1255I
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P08069.M1255I

Detailed results for job #oncokb produced by ELASPIC
P08069, Insulin-like growth factor 1 receptor:
M1255I
1
1367
Pkinase_Tyr
Furin-like
fn3
Recep_L_do..
Recep_L_domain

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P08069.M1255I

Completed successfully

Protein, domain: P08069 Pkinase_Tyr

Type: Core (stability)

PDB template used: 3lvp_B

Seq identity: 1.000 Model score: -0.882

ELASPIC ΔΔG: 0.808

ELASPIC2 (EL2) score: 0.035

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.