ELASPIC home << Job #oncokb << P07949.S904F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P07949.S904F

Detailed results for job #oncokb produced by ELASPIC
P07949, Proto-oncogene tyrosine-protein kinase receptor Ret:
S904F
1
1114
Pkinase_Tyr
Cadhe..
MK14 isoform 4, Isoform Exip of Mitogen-activated protein kinase 14:
1
307
Pkinase
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P07949.S904F

Completed successfully

Protein, domain: P07949 Pkinase_Tyr

Interacting with: MK14 isoform 4 Pkinase

PDB templates used: 4lop_C, 4lop_A

Seq identity: 0.257, 0.996 Model score: 0.759

ELASPIC ΔΔG: 2.156

ELASPIC2 (EL2) score: 0.200

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.