ELASPIC home << Job #oncokb << P06400.W563L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P06400.W563L

Detailed results for job #oncokb produced by ELASPIC
P06400, Retinoblastoma-associated protein:
W563L
1
928
DUF3452
RB_A
RB_B+Rb_C
RBL1, Retinoblastoma-like protein 1:
1
1068
DUF3452
RB_A
RB_B+Rb_C
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Protein: P06400 | RBL1 | Cofactors | All
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P06400.W563L

Completed successfully

Protein, domain: P06400 RB_A

Interacting with: RBL1 RB_B+Rb_C

PDB templates used: 1gux_A, 1gux_B

Seq identity: 0.894, 0.324 Model score: 0.213

ELASPIC ΔΔG: 1.825

ELASPIC2 (EL2) score: 0.289

Mutation in databases: COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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