ELASPIC home << Job #oncokb << P04637.R248W
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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P04637.R248W

Detailed results for job #oncokb produced by ELASPIC
P04637, Cellular tumor antigen p53:
R248W
1
393
P53_TAD
P53+P53_tetramer
TP63, Tumor protein 63:
1
680
P53+P53_tetramer
SAM_2
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Protein: P04637 | TP63 | Cofactors | All
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P04637.R248W

Completed successfully

Protein, domain: P04637 P53+P53_tetramer

Interacting with: TP63 P53+P53_tetramer

PDB templates used: 4ibt_B, 4ibt_A

Seq identity: 0.990, 0.553 Model score: 0.602

ELASPIC ΔΔG: 1.302

ELASPIC2 (EL2) score: 0.960

Mutation in databases: UniProt, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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