ELASPIC home << Job #oncokb << P04637.R181L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P04637.R181L

Detailed results for job #oncokb produced by ELASPIC
P04637, Cellular tumor antigen p53:
R181L
1
393
P53_TAD
P53+P53_tetramer
NFKBIA, NF-kappa-B inhibitor alpha:
1
317
Ank
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Model: Wild-type | Mutant | Both
Protein: P04637 | NFKBIA | Cofactors | All
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P04637.R181L

Completed successfully

Protein, domain: P04637 P53+P53_tetramer

Interacting with: NFKBIA Ank

PDB templates used: 1ycs_A, 1ycs_B

Seq identity: 1.000, 0.391 Model score: 1.173

ELASPIC ΔΔG: 1.257

ELASPIC2 (EL2) score: 0.133

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.