ELASPIC home << Job #oncokb << P04637.D186A
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P04637.D186A

Detailed results for job #oncokb produced by ELASPIC
P04637, Cellular tumor antigen p53:
D186A
1
393
P53_TAD
P53+P53_tetramer
EHMT1 isoform 3, Isoform 3 of Histone-lysine N-methyltransferase EHMT1:
1
1184
SET
Ank_2+Ank_2+Ank
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P04637.D186A

Completed successfully

Protein, domain: P04637 P53+P53_tetramer

Interacting with: EHMT1 isoform 3 Ank_2+Ank_2+Ank

PDB templates used: 1ycs_A, 1ycs_B

Seq identity: 1.000, 0.394 Model score: 0.783

ELASPIC ΔΔG: 2.524

ELASPIC2 (EL2) score: 0.307

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.