ELASPIC home << Job #oncokb << P04637.C176F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P04637.C176F

Detailed results for job #oncokb produced by ELASPIC
P04637, Cellular tumor antigen p53:
C176F
1
393
P53_TAD
P53+P53_tetramer
TP73, Tumor protein p73:
1
636
P53+P53_tetramer
SAM_2
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Model: Wild-type | Mutant | Both
Protein: P04637 | TP73 | Cofactors | All
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P04637.C176F

Completed successfully

Protein, domain: P04637 P53+P53_tetramer

Interacting with: TP73 P53+P53_tetramer

PDB templates used: 4guq_B, 4guq_A

Seq identity: 0.584, 0.995 Model score: -0.206

ELASPIC ΔΔG: 3.364

ELASPIC2 (EL2) score: -0.191

Mutation in databases: UniProt, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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