ELASPIC home << Job #oncokb << P04626.Y803N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P04626.Y803N

Detailed results for job #oncokb produced by ELASPIC
P04626, Receptor tyrosine-protein kinase erbB-2:
Y803N
1
1255
Recep_L_..
Pkinase_Tyr
Furin-like
GF_rec..
Recep_L_..
ANKS1A, Ankyrin repeat and SAM domain-containing protein 1A:
1
1134
Ank
SA..
SA..
PID
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Protein: P04626 | ANKS1A | Cofactors | All
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P04626.Y803N

Completed successfully

Protein, domain: P04626 Pkinase_Tyr

Interacting with: ANKS1A Ank

PDB templates used: 1blx_A, 1blx_B

Seq identity: 0.268, 0.310 Model score: 0.900

ELASPIC ΔΔG: 1.795

ELASPIC2 (EL2) score: -0.257

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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