ELASPIC home << Job #oncokb << P04626.S335C
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P04626.S335C

Detailed results for job #oncokb produced by ELASPIC
P04626, Receptor tyrosine-protein kinase erbB-2:
S335C
1
1255
Recep_L_..
Pkinase_Tyr
Furin-like
GF_rec..
Recep_L_..
EGFR isoform 4, Isoform 4 of Epidermal growth factor receptor:
1
628
Recep_L_domain
Recep_L_domain
Furin-like
G..
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P04626.S335C

Completed successfully

Protein, domain: P04626 Furin-like

Interacting with: EGFR isoform 4 Furin-like

PDB templates used: 1mox_A, 1mox_B

Seq identity: 0.490, 1.000 Model score: 0.900

ELASPIC ΔΔG: 0.794

ELASPIC2 (EL2) score: 0.352

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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