ELASPIC home << Job #oncokb << P04049.S427G
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P04049.S427G

Detailed results for job #oncokb produced by ELASPIC
P04049, RAF proto-oncogene serine/threonine-protein kinase:
S427G
1
648
RBD
C1_1
Pkinase_Tyr

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P04049.S427G

Completed successfully

Protein, domain: P04049 Pkinase_Tyr

Type: Core (stability)

PDB template used: 3omv_A

Seq identity: 1.000 Model score: -0.271

ELASPIC ΔΔG: -0.177

ELASPIC2 (EL2) score: 1.645

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.