ELASPIC home << Job #oncokb << P03372.S432L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P03372.S432L

Detailed results for job #oncokb produced by ELASPIC
P03372, Estrogen receptor:
S432L
1
595
zf-C4+Hormone_recep
THB isoform 2, Isoform Beta-2 of Thyroid hormone receptor beta:
1
476
zf-C4+Hormone_recep
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P03372.S432L

Completed successfully

Protein, domain: P03372 zf-C4+Hormone_recep

Interacting with: THB isoform 2 zf-C4+Hormone_recep

PDB templates used: 3uvv_B, 3uvv_A

Seq identity: 0.302, 0.838 Model score: 0.743

ELASPIC ΔΔG: -0.271

ELASPIC2 (EL2) score: 0.482

Mutation run by user.

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Citation

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