ELASPIC home << Job #oncokb << P03372.L536H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P03372.L536H

Detailed results for job #oncokb produced by ELASPIC
P03372, Estrogen receptor:
L536H
1
595
zf-C4+Hormone_recep
NR0B1 isoform 2, Isoform 2 of Nuclear receptor subfamily 0 group B member 1:
1
400
Hormone_recep
Select affected interaction:

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P03372.L536H

Completed successfully

Protein, domain: P03372 zf-C4+Hormone_recep

Interacting with: NR0B1 isoform 2 Hormone_recep

PDB templates used: 3r2a_B, 3r2a_C

Seq identity: 0.315, 0.252 Model score: 2.034

ELASPIC ΔΔG: 1.999

ELASPIC2 (EL2) score: 0.783

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.