ELASPIC home << Job #oncokb << P01116.Y32S
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01116.Y32S

Detailed results for job #oncokb produced by ELASPIC
P01116, GTPase KRas:
Y32S
1
189
Ras
GNDS isoform 2, Isoform 2 of Ral guanine nucleotide dissociation stimulator:
1
951
RasGEF
Select affected interaction:

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P01116.Y32S

Completed successfully

Protein, domain: P01116 Ras

Interacting with: GNDS isoform 2 RasGEF

PDB templates used: 4nyi_R, 4nyi_S

Seq identity: 0.940, 0.247 Model score: -0.386

ELASPIC ΔΔG: 2.926

ELASPIC2 (EL2) score: 2.501

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.