ELASPIC home << Job #oncokb << P01112.T58I
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01112.T58I

Detailed results for job #oncokb produced by ELASPIC
P01112, GTPase HRas:
T58I
1
189
Ras
TIAM1, T-lymphoma invasion and metastasis-inducing protein 1:
1
1591
RhoGEF
PDZ
PH
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Protein: P01112 | TIAM1 | Cofactors | All
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P01112.T58I

Completed successfully

Protein, domain: P01112 Ras

Interacting with: TIAM1 RhoGEF

PDB templates used: 2dfk_B, 2dfk_A

Seq identity: 0.333, 0.332 Model score: -0.495

ELASPIC ΔΔG: 1.256

ELASPIC2 (EL2) score: 1.570

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.