ELASPIC home << Job #oncokb << P01112.Q61L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01112.Q61L

Detailed results for job #oncokb produced by ELASPIC
P01112, GTPase HRas:
Q61L
1
189
Ras
RABX5 isoform 3, Isoform 3 of Rab5 GDP/GTP exchange factor:
1
531
VPS9
z..
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P01112.Q61L

Completed successfully

Protein, domain: P01112 Ras

Interacting with: RABX5 isoform 3 VPS9

PDB templates used: 2ot3_B, 2ot3_A

Seq identity: 0.309, 1.000 Model score: -1.363

ELASPIC ΔΔG: 2.236

ELASPIC2 (EL2) score: 2.328

Mutation in databases: UniProt, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.