ELASPIC home << Job #oncokb << P01112.P34R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01112.P34R

Detailed results for job #oncokb produced by ELASPIC
P01112, GTPase HRas:
P34R
1
189
Ras
RAF1, RAF proto-oncogene serine/threonine-protein kinase:
1
648
RBD
C1_1
Pkinase_Tyr
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Protein: P01112 | RAF1 | Cofactors | All
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P01112.P34R

Completed successfully

Protein, domain: P01112 Ras

Interacting with: RAF1 RBD

PDB templates used: 4g0n_A, 4g0n_B

Seq identity: 0.988, 1.000 Model score: -1.295

ELASPIC ΔΔG: 1.761

ELASPIC2 (EL2) score: 2.300

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.