ELASPIC home << Job #oncokb << P01111.T58I
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01111.T58I

Detailed results for job #oncokb produced by ELASPIC
P01111, GTPase NRas:
T58I
1
189
Ras
GRP2 isoform 2, Isoform 2 of RAS guanyl-releasing protein 2:
1
671
C1_1
RasGEF
EF-hand_5
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P01111.T58I

Completed successfully

Protein, domain: P01111 Ras

Interacting with: GRP2 isoform 2 RasGEF

PDB templates used: 4nyi_R, 4nyi_S

Seq identity: 0.916, 0.215 Model score: 0.035

ELASPIC ΔΔG: 0.996

ELASPIC2 (EL2) score: 1.446

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.