ELASPIC home << Job #oncokb << P01111.Q61R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01111.Q61R

Detailed results for job #oncokb produced by ELASPIC
P01111, GTPase NRas:
Q61R
1
189
Ras
RACGAP1, Rac GTPase-activating protein 1:
1
632
C1_1+RhoGAP
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Model: Wild-type | Mutant | Both
Protein: P01111 | RACGAP1 | Cofactors | All
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P01111.Q61R

Completed successfully

Protein, domain: P01111 Ras

Interacting with: RACGAP1 C1_1+RhoGAP

PDB templates used: 1ow3_B, 1ow3_A

Seq identity: 0.307, 0.336 Model score: -0.197

ELASPIC ΔΔG: -0.339

ELASPIC2 (EL2) score: 2.936

Mutation in databases: UniProt, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.