ELASPIC home << Job #oncokb << P00533.L861Q
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P00533.L861Q

Detailed results for job #oncokb produced by ELASPIC
P00533, Epidermal growth factor receptor:
L861Q
1
1210
Recep_L_d..
Recep_..
Furin..
Pkinase_Tyr
CISH isoform 2, Isoform 1B of Cytokine-inducible SH2-containing protein:
1
264
SH2
SOCS_box
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P00533.L861Q

Completed successfully

Protein, domain: P00533 Pkinase_Tyr

Interacting with: CISH isoform 2 SH2

PDB templates used: 4gl9_A, 4gl9_E

Seq identity: 0.344, 0.461 Model score: 1.049

ELASPIC ΔΔG: 0.871

ELASPIC2 (EL2) score: 0.129

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.