ELASPIC home << Job #oncokb << P00533.E931G
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P00533.E931G

Detailed results for job #oncokb produced by ELASPIC
P00533, Epidermal growth factor receptor:
E931G
1
1210
Recep_L_d..
Recep_..
Furin..
Pkinase_Tyr
ABL2 isoform 10, Isoform 10 of Abelson tyrosine-protein kinase 2:
1
1064
F_act..
Pkinase_Tyr
SH..
SH2
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P00533.E931G

Completed successfully

Protein, domain: P00533 Pkinase_Tyr

Interacting with: ABL2 isoform 10 Pkinase_Tyr

PDB templates used: 4lrm_A, 4lrm_B

Seq identity: 0.990, 0.399 Model score: -0.229

ELASPIC ΔΔG: 1.408

ELASPIC2 (EL2) score: 1.385

Mutation run by user.

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Citation

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