ELASPIC home << Job #oncokb << O96028.E1099K
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

O96028.E1099K

Detailed results for job #oncokb produced by ELASPIC
O96028, Histone-lysine N-methyltransferase NSD2:
E1099K
1
1365
SET
PWWP
HM..
PWWP
..
NSD2 isoform 4, Isoform 4 of Histone-lysine N-methyltransferase NSD2:
1
584
SET
PWWP
PHD
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O96028.E1099K

Completed successfully

Protein, domain: O96028 SET

Interacting with: NSD2 isoform 4 SET

PDB templates used: 3kma_A, 3kma_B

Seq identity: 0.243, 0.243 Model score: 0.438

ELASPIC ΔΔG: 1.384

ELASPIC2 (EL2) score: -0.262

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.