ELASPIC home << Job #oncokb << O96017.S428F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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O96017.S428F

Detailed results for job #oncokb produced by ELASPIC
O96017, Serine/threonine-protein kinase Chk2:
S428F
1
543
FHA
Pkinase
DBF4, Protein DBF4 homolog A:
1
674
zf-DBF
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Protein: O96017 | DBF4 | Cofactors | All
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O96017.S428F

Completed successfully

Protein, domain: O96017 Pkinase

Interacting with: DBF4 zf-DBF

PDB templates used: 4f9c_A, 4f9c_B

Seq identity: 0.289, 1.000 Model score: 0.765

ELASPIC ΔΔG: 0.918

ELASPIC2 (EL2) score: -0.712

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

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